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assessment of Cas9-driven genome editing in presence of DNA oligos in CML cells

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NIAID Data Ecosystem2026-03-13 收录
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We assessed indels resulting from Cas9-induced genome editing in CML cells in the presence of guide-complementary DNA oligonucleotides intended to inhibit Cas9 activity. We amplified pre-determined loci that were target with the supplied guides or were expected to be off-target sites for these guides. The on-target loci are EMX1 and FANCF.

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2022-01-14
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