KRasG12C ligand complex
收藏Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7o70
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KRasG12C ligand complex Descriptor: 1-[(4R,7S)-12-chloro-14-fluoro-13-(2-fluoro-6-hydroxyphenyl)-4-methyl-10-oxa-2,5,16,18-tetrazatetracyclo[9.7.1.0^(2,7).0^(15,19)]nonadeca-1(18),11,13,15(19),16-pentaen-5-en-1-one-yl]prop-2, CALCIUM ION, GTPase KRas, ... Authors: Phillips, C. Deposit date: 2021-04-12 Release date: 2022-04-20 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.18 Å) Cite: Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRAS G12C . J.Med.Chem., 65, 2022
创建时间：
2021-04-12
