相关数据集
Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations
Polycomb repressive complex 2 (PRC2) is an important regulator of cellular differentiation and cell type identity. Overexpression or activating mutations of EZH2, the catalytic component of the PRC2 c
NIAID Data Ecosystem70
Supplementary Table S6 from Differential DNA Methylation in the Benign and Cancerous Prostate Tissue of African American and European American Men
Supplementary Table S6 shows genes identified in both AA and EA, based on differentially methylated CpGs, which were previously identified as oncogenes.
NIAID Data Ecosystem50
Targeting serotonin-driven histone serotonylation suppresses lineage plasticity and progression of NEPC
Neuroendocrine prostate cancer (NEPC) is an aggressive, therapy-resistant subtype of prostate cancer characterized by lineage plasticity. While metabolic and signaling molecules are increasingly recog
NIAID Data Ecosystem30
DNA methylation profiles in gastric mucosa samples with low, intermediate and high cancer risk. DNA methylation profiles in gastric mucosa samples with low, intermediate and high cancer risk
DNA methylation profiles were compared between gastric mucosae samples without Helicobacter pylori (HP) infection (low risk : G1), those with HP eradication without gastric cancer (intermediate risk :
NIAID Data Ecosystem70
DNA methylation analysis in oropharyngeal cancer [450K array]. DNA methylation analysis in oropharyngeal cancer [450K array]
DNA methylation analysis in oropharyngeal squamous carcinoma (OPSCC) samples and oropharyngeal non-cancerous mucosa samples. Infinium HumanMethylation450 BeadChip was used to obtain DNA methylation pr
NIAID Data Ecosystem50
