Percentage of integration sites residing within gene coding regions/CpG islands in vitro and in vivo

The proportion of HTLV-1 integration sites lying within a CpG island or the coding region of a gene (as defined by specified databases) in cell culture in vitro and in persistent infection in vivo were compared to the proportion of Matched Random Control (MRC) sites derived in silico (see Materials and Methods).. Human gene annotation tables from the UCSC genome database include Acembly genes, GenScan genes, Known genes, RefSeq genes, Unigene and Ensembl genes. * indicates a significant difference between the HTLV-1 proviral dataset and MRCs (p$ and �� indicate a significant difference between in vivo and in vitro HTLV-1 proviral datasets (p