S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand.
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S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA substrate containing a 60 nucleotide lagging strand. Descriptor: Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha catalytic subunit A, ... Authors: Jones, M.L, Yeeles, J.T.P. Deposit date: 2022-10-05 Release date: 2023-08-09 Last modified: 2023-08-30 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: How Pol alpha-primase is targeted to replisomes to prime eukaryotic DNA replication. Mol.Cell, 83, 2023
酿酒酵母(S. cerevisiae)复制体(replisome)结合Ctf4蛋白,并与DNA聚合酶α-引物酶(pol α primase)结合。 该复合物结合了带有60核苷酸滞后链的叉状DNA底物。 组分说明:细胞分裂控制蛋白45(Cell division control protein 45)、减数分裂染色体分离蛋白3(Chromosome segregation in meiosis protein 3)、DNA聚合酶α催化亚基A(DNA polymerase alpha catalytic subunit A)…… 作者:琼斯(Jones, M.L.)、耶利斯(Yeeles, J.T.P.) 提交日期:2022-10-05 发布日期:2023-08-09 最后修改日期:2023-08-30 实验方法:电子显微镜(3.5埃) 引用文献:《DNA聚合酶α-引物酶如何靶向复制体以启动真核生物DNA复制》,《分子细胞》(Mol. Cell),第83卷,2023年



