five

FGFR1 in complex with ponatinib (co-crystallisation).

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4v01
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FGFR1 in complex with ponatinib (co-crystallisation). Descriptor: 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, ... Authors: Tucker, J, Klein, T, Breed, J, Breeze, A, Overman, R, Phillips, C, Norman, R.A. Deposit date: 2014-09-10 Release date: 2014-12-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4 Structure, 22, 2014
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2014-09-10
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