An intestine-specific Scd1 knockout model was developed by crossing Scd1 fl/fl mice with mice expressing Cre recombinase under the control of the Villin promote
A,B. Body weights of the 1-wk study (Fig. 3A-D). C. Body weights for the 4-week and 8-week study (Fig. 3E-L). D. Liver gene expression of 1-wk treatment with PF-04991532. E-G. Plasma insulin of drug t