Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 2500 ms

Structure of serine-beta-lactamase CTX-M-14 following the time-resolved active site binding of boric acid and subsequent glycerol-boric acid-ester formation, 2500 ms Descriptor: BORATE ION, Beta-lactamase, SULFATE ION, ... Authors: Prester, A, Perbandt, M, Galchenkova, M, Oberthuer, D, Yefanov, O, Hinrichs, W, Rohde, H, Betzel, C. Deposit date: 2023-06-11 Release date: 2024-06-26 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Time-resolved crystallography of boric acid binding to the active site serine of the beta-lactamase CTX-M-14 and subsequent 1,2-diol esterification. Commun Chem, 7, 2024

丝氨酸β-内酰胺酶（serine-beta-lactamase）CTX-M-14在硼酸以时间分辨模式结合其活性位点并后续形成甘油-硼酸酯后的结构（2500毫秒）。描述项：硼酸根离子（borate ion）、β-内酰胺酶、硫酸根离子（sulfate ion）……。作者：Prester, A、Perbandt, M、Galchenkova, M、Oberthuer, D、Yefanov, O、Hinrichs, W、Rohde, H、Betzel, C。提交日期：2023-06-11；发布日期：2024-06-26；最后修改日期：2024-11-13。实验方法：X射线衍射（1.55 Å）。引用文献：硼酸结合β-内酰胺酶CTX-M-14活性位点丝氨酸及后续1,2-二醇酯化反应的时间分辨晶体学研究。Commun Chem，第7卷，2024年。