Crystal structure of B. anthracis DHPS with compound 11: (E)-N-[4-(trifluoromethyl)benzyl]-1-[4-(trifluoromethyl)phenyl]methanimine

Crystal structure of B. anthracis DHPS with compound 11: (E)-N-[4-(trifluoromethyl)benzyl]-1-[4-(trifluoromethyl)phenyl]methanimine Descriptor: (E)-N-[4-(trifluoromethyl)benzyl]-1-[4-(trifluoromethyl)phenyl]methanimine, Dihydropteroate Synthase, SULFATE ION Authors: Hammoudeh, D.I, White, S.W. Deposit date: 2013-11-13 Release date: 2014-05-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase. Acs Chem.Biol., 9, 2014

炭疽芽孢杆菌（Bacillus anthracis，缩写B. anthracis）二氢蝶酸合酶（Dihydropteroate Synthase, DHPS）与化合物11的共晶结构：(E)-N-[4-(三氟甲基)苄基]-1-[4-(三氟甲基)苯基]甲亚胺。描述符：(E)-N-[4-(三氟甲基)苄基]-1-[4-(三氟甲基)苯基]甲亚胺、二氢蝶酸合酶（Dihydropteroate Synthase）、硫酸根离子（SULFATE ION）。作者：Hammoudeh, D.I.、White, S.W.。提交日期：2013-11-13；发布日期：2014-05-14；最后修改日期：2023-09-20。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.3埃（Å）。引用文献：《二氢蝶酸合酶变构抑制位点的鉴定与表征》（*Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase*），发表于《ACS Chemical Biology》，第9卷，2014年。