CD40-mediated amplification of local immunity by keratinocytes in impaired by HPV

ChEBI2015-10-26 更新2026-07-12 收录

免疫逃逸机制

角质形成细胞免疫调节

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-54181 数据链接链接失效反馈

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CD40-mediated amplification of local immunity by keratinocytes in impaired by HPV

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2015-10-26

DENR controls JAK2 translation to induce PD-L1 expression for tumor immune evasion

免疫逃逸机制

PD-L1调控

To identify the potential signaling pathway involved in DENR KO cells upon PD-L1 production, we harvested IFNγ-treated control and DENR KO cells for RNA-seq. Bioinformatic analysis of the RNA-seq data

NIAID Data Ecosystem90

A study of Qianqian Li et.al.

病毒变体功能表征

免疫逃逸机制

No higher infectivity but immune escape of SARS-CoV-2 501Y.V2 variants The 501Y.V2 variants of SARS-CoV-2 containing multiple mutations in Spike are now dominant in South Africa and are rapidly spread

Mendeley Data2021-03-09 更新40

Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

免疫逃逸机制

细胞功能调控

Immune evasion is now recognized as a key feature of cancer progression. In animal models, the activity of cytotoxic lymphocytes is suppressed in the tumour microenvironment by the immunosuppressive c

Figshare2016-01-18 更新40

Gli2 Facilitates Tumor Immune Evasion and Immunotherapeutic Resistance by Coordinating Wnt Ligand and Prostaglandin Synthesis [scRNAseq]

免疫逃逸机制

免疫治疗联合策略

Therapeutic resistance to immune checkpoint blockade remains a prevalent obstacle across many cancer types, and an improved mechanistic understanding of this process could lead to effective combinatio

NIAID Data Ecosystem60

Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity

免疫逃逸机制

表观遗传调控

Isocitrate Dehydrogenase 1 (IDH1) is the most commonly mutated metabolic gene across human cancers. Mutant IDH1 (mIDH1) generates the oncometabolite (R)-2-hydroxyglutarate, disrupting enzymes involved

DataONE2024-04-30 更新40

CD40-mediated amplification of local immunity by keratinocytes in impaired by HPV

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