Lytic Transglycosylase MltD of Pseudomonas aeruginosa in a ternary complex bound to Bulgecin A and chito-tetraose

Lytic Transglycosylase MltD of Pseudomonas aeruginosa in a ternary complex bound to Bulgecin A and chito-tetraose Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE, ... Authors: Miguel-Ruano, V, Hermoso, J.A. Deposit date: 2023-12-15 Release date: 2024-04-17 Last modified: 2024-04-24 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Structural characterization of lytic transglycosylase MltD of Pseudomonas aeruginosa, a target for the natural product bulgecin A. Int.J.Biol.Macromol., 267, 2024

铜绿假单胞菌（Pseudomonas aeruginosa）裂解转糖基酶MltD与Bulgecin A及几丁四糖（chito-tetraose）结合形成的三元复合物。
配体描述：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、4-O-(4-O-磺酰基-N-乙酰葡糖胺基)-5-甲基羟基-L-脯氨酸-牛磺酸，……
作者：Miguel-Ruano, V、Hermoso, J.A.
存储日期：2023-12-15
发布日期：2024-04-17
最后修改日期：2024-04-24
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.98埃（Å）
引用文献：《铜绿假单胞菌裂解转糖基酶MltD的结构表征——天然产物Bulgecin A的作用靶点》，Int. J. Biol. Macromol.，第267卷，2024年