ACR response and withdrawal probability of treatments.
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NA: Not applicable.#It was calculated by weighted average methods: (Response1 × n1 + Response2 × n2)/(n1+n2). Response1 and Response2 were indicated as the response in control arm of trial 1 and 2, and n1 and n2 were the patient number, respectively. [14], [15].*Adjusted response = RP + (1-RP) × ([TT-TP]/[1-TP]), RP, TT and TP was indicated for the response of reference placebo, trial treatment, and trial placebo, respectively. [10].&Withdraw probability (t) = 1 – exp(λ× (t–1) γ–λ×tγ). In this formula, t was indicated as the current cycle number, and λ and γ were scale and shape parameters, respectively.
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2015-12-02



