Median mutation rates for the indicated MLH1-PMS1 combinations.
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The S288c strain EAY1365 was transformed with ARS CEN plasmids containing MLH1 and PMS1 from the indicated strains (Table 1). Mutation rates (mutations per cell per generation) were determined using the lys2::insE-A14 reversion assay as described in the Materials and Methods. For each strain, 15�C30 independent cultures, from three to six independent transformants, were assayed. See Figure 2 for class groupings. 95% C. I. = 95% confidence interval.
创建时间：
2015-12-02
