Slow-digesting carbohydrates and microbiome

The present bioproject aimed to investigate the effects of changing the quality of carbohydrates from rapidly to slowly digestible carbohydrates on gut microbiota composition and functional pathway profiles in growing rats fed a high-fat diet (HFD). Growing rats were fed on an HFD containing carbohydrates with different digestion rates: an HFD containing rapid-digesting carbohydrates (OBE group) or slow-digesting carbohydrates (ISR group), for 4 weeks. A non-obese group (NOB) was included as a reference and rats were fed on a rodent standard diet (AIN93G). The composition of gut microbiota was analyzed by 16S rRNA-based metagenomics