SNP Allocation For Estimating Heritability (SAFE-<i>h</i>²): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects

SAFE-<i>h</i>²is developed under an academic research study to provide proper estimates of SNP heritability. For this, SAFE-<i>h</i>²creates heritability profiles to prevent SNPs with illogical negative contributions to heritability. It also minimizes the contributions by false-positive SNP hits. Finally, SAFE-<i>h</i>² can perform a joint analysis on both additive and non-additive allelic effects. Therefore, it also provides the chance for GWASs to perform linear association tests while capturing both additive and non-additive effects.<b>Software Availability:</b> SAFE-<i>h</i>²(SNP Allocation For Estimating Heritability)<b> </b>contains the compiled SAFE-<i>h</i>² scripts with related installation and usage manual (Download link: https://github.com/SAFE-h2/SAFE-h2).Read the related research article “<b>SNP Allocation For Estimating Heritability (SAFE-</b><b><i>h</i></b>^{<strong>2</strong>}<b>): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects” (doi:</b> https://doi.org/10.1101/2023.08.28.555092<b>)</b> for the full study and descriptions.<b>Citation: </b><i>Behrooz Darbani, Mogens Nicolaisen. </i>SNP Allocation For Estimating Heritability (SAFE-<i>h</i>²): A tool to explore genomic origins of phenotypes for estimation of SNP heritability using additive-only allelic effects or additive and non-additive allelic effects. doi: https://doi.org/10.1101/2023.08.28.555092<b>Contact: [e-mail], [e-mail]</b>Department of Agroecology, Faculty of Technical Sciences, Aarhus University, Slagelse, Denmark