SNPs (p−5) associated with in vitro HIV-1 replication in monocyte-derived macrophages.

Chr., chromosome.*1The effect of the SNP in DYRK1A was replicated with monocyte-derived macrophages from an independent group of 31 donors.*2Empirical p value calculated for linear regression using 107 permutations of the genotypes.*3Measure for the magnitude of linkage disequilibrium (r2) between SNPs with identical symbols (▴, ◂, ▸, ▾, ▪, • or ⧫).*4Major genotype is the heterozygous genotype (∼50%); both classes of homozygous genotypes equally present (∼25% each).