DialySPARC™: Bio-Integrated Dialysis System with Modular Filter Replacement and Tissue Integration

The DialySPARC™ system is a novel bio-integrated dialysis solution designed to replace or augment traditional renal filtration by combining tissue-engineered scaffolds, modular filtration units, and integrated AI monitoring. This Figshare entry includes the provisional patent filing (USPTO #63/816,503), the DialySPARC MVP development plan, technical system overview, and system flowchart to document the full scope of the innovation. The device architecture emphasizes modular filter replacement, outpatient accessibility, and enhanced biocompatibility through tissue integration, with the potential to revolutionize renal support and patient outcomes.<br>Key performance targets include:- Clearance efficacy of Kt/V ≥2.0 per week -Flow rates of 10–50 mL/min-Operational lifespan of 30–90 days per filter unit -AI-enabled monitoring for continuous feedback and safe outpatient maintenance.These materials provide a comprehensive technical package for reviewers, investors, and grant reviewers to evaluate and support the DialySPARC system’s transformative potential.<br>