Mean methadone dose, <i>(R)</i>-, <i>(S)-</i> and <i>(R,S)-</i>methadone plasmatic concentrations by phenotype of <i>CYP2D6</i> in the responder and nonresponder patients.
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aData from the 105 patients included. bBold numbers indicate statistically significant differences between patients. cPlasma concentrations were obtained for 79 patients. dStatistical significant differences were found between Ultrarapid compared to Extensive metabolizers (Tukey post hoc analisys) p<0.05.
创建时间:
2011-05-12



