Bos taurus breed:Holstein Epigenomics

Epigeneitc modification plays a critical role many biological processes, however, little is known about the epigenetic regulatory mechanisms in dairy cattle for milk production traits, such as DNA methylation. Whole genome bisulfite sequencing (WGBS) was employed to detect differential methylation genes in blood samples in dry period and lactation period between two groups of cows with extremely high (H group) and low (L group) phenotypic values of milk production traits.