An Efficient Synthesis Strategy to the Core Structure of 6–5–6–5–6-Membered Epipolythiodiketopiperazines

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https://figshare.com/articles/dataset/An_Efficient_Synthesis_Strategy_to_the_Core_Structure_of_6_5_6_5_6_Membered_Epipoly_thiodiketo_pipera_zines/2285539 数据链接链接失效反馈

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A concise route to the core structure 1 of 6–5–6–5–6-membered epipolythiodiketopiperazines is described. The strategy relies on construction of the pyrrolines by double nucleophilic opening of a bis(oxabicyclo[2.2.1]heptene) 2, obtained after bidirectional condensation of N,N′-diacetyldiketopiperazine (4) with aldehyde 3.

创建时间：

2014-06-06

An Efficient Synthesis Strategy to the Core Structure of 6–5–6–5–6-Membered Epipoly­thiodiketo­pipera­zines

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An Efficient Synthesis Strategy to the Core Structure of 6–5–6–5–6-Membered Epipolythiodiketopiperazines