Diospyros kaki

The behavioural and biochemical assesment results are mentioned with graphs in the excel sheet. In rats with stress-induced depression, both the extracts of ethanol (200 mg/kg) and aqueous (200 mg/kg) given orally showed improvement in depressive symptoms. These benefits were evidenced by a significant (P&lt;0.05) decrease in immobility time in both the tail suspension and the forced swimming tests, a significant (P&lt;0.05) increase in sucrose consumption in the sucrose preference test, and a rise in rearing and crossing during the test in the open field. Furthermore, the extracts led to decreased levels of monoamine oxidase A and B (P0.05), reduced MDA levels (P0.05), and improved superoxide dismutase and Glutathione-S-transferase activity when compared with CUS depressive rats and the standard treatment Impramine (15 mg/kg).行为学与生化学评估结果已随图表收录于Excel表格中。在应激性抑郁大鼠模型中，经口给予200mg/kg的乙醇提取物与200mg/kg的水提取物，均可改善其抑郁样症状。该干预的获益可通过以下指标得到验证：悬尾实验（tail suspension test）与强迫游泳实验（forced swimming test）中大鼠的不动时间均显著缩短（P<0.05）；蔗糖偏好实验（sucrose preference test）中蔗糖摄取量显著升高（P<0.05）；旷场实验（open field test）中大鼠的直立探索行为与跨格运动行为均有所增加。此外，与慢性不可预知温和应激（CUS）抑郁大鼠及阳性对照药物丙咪嗪（Impramine，15mg/kg）相比，两种提取物均可显著降低单胺氧化酶A与B的活性（P<0.05）、降低丙二醛（MDA）水平（P<0.05），并提升超氧化物歧化酶（superoxide dismutase）与谷胱甘肽S-转移酶（Glutathione-S-transferase）的活性。