HUVEC molQTL resource: ATAC-seq QTL summary statistics (GRCh38)

ATAC-seq QTL summary statistics

If you use this dataset, please cite the manuscript in order to fairly acknowledge the contribution of all participating studies and their sponsors.

Study overview

This repository provides access to ATAC-seq quantitative trait loci GWAS summary statistics generated in the study:

Dissecting the Cellular Genetics of Cardiovascular Disease Through Endothelial and Immune Compartments ProfilingStephen Watt, Matiss Ozols, Arianna Landini, Bin Liu, Sodbo Sharapov, Daniela Zanotti, Gabriela Ivanova, Charles Solomon, Xu Dong Yang, Tolulope Balogun, Nicole Staudt, Wei Li, Fatin Al-Janabi, Tom R. Webb, David G. McVey, Nicholas Morrell, Martin Bennett, Nilesh J. Samani, Stefan Gräf, Shu Ye, Nicola Pirastu, Nicole Soranzo, Mattia FrontinibioRxiv 2025.11.10.687750; doi: https://doi.org/10.1101/2025.11.10.687750

This dataset represents one component of a larger multi-omic resource. See the main Zenodo record for the complete collection: DOI 10.5281/zenodo.19480929

Files and organisation

README.md: definitions of all columns in the summary statistics files

ATAC.tar: archive containing GWAS summary statistics, provided as one gzipped, tab-separated file per autosomal chromosome (22 files total).

ATAC_cis_eQTLs_chr<chromosome>.tsv.gz (e.g. ATAC_cis_eQTLs_chr1.tsv.gz): each row represents a single variant–trait association, with molecular traits identified by the trait column. Genomic coordinates are based on GRCh38.