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Bulk RNA-sequencing analysis of isogenic murine Kras/p53 (KP) Brg1 wildtype cells versus Brg1 knockout (KPB) cells

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NIAID Data Ecosystem2026-03-12 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP271459
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资源简介:
The goals of this experiment is to identify transcriptomic changes upon loss of Brg1 in lung adenocarcinoma cells. Overall design: Kras/p53 lung adenocarcinoma tumor derived cell lines were subjected to CRISRP/Cas9-mediated genome editing using guides against sgTomato (control) or sgBrg1 (sample). Isogenic Kras/p53 mutant lung cancer cell lines with and without Brg1 were derived and used for bulk RNA-sequencing. Experiment was performed in triplicate conditions.
创建时间:
2020-09-17
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