To identify lncRNAs involved in regulating PMN-MDSCs, an Arraystar lncRNA microarray was performed to determine the lncRNA expression profile in PMN-MDSCs. Compared to those in CD11b+Ly6G+ cells under

NIAID Data Ecosystem40

Identification of SLAMF3 (CD229) as an Inhibitor of Hepatocellular Carcinoma Cell Proliferation and Tumour Progression

癌症分子靶点

肿瘤免疫调节

Although hepatocellular carcinoma (HCC) is one of the most common malignancies and constitutes the third leading cause of cancer-related deaths, the underlying molecular mechanisms are not fully under

NIAID Data Ecosystem30

Role of Tim-3 on tumoral Treg cells

肿瘤免疫调节

Treg细胞功能

A gene profiling study revealed the requirement of Tim-3 in upregulation of effector Treg genes encoding immune inhibitory molecules, chemokine receptors for tissue residency, chemokines, and cytokine

NIAID Data Ecosystem50

Impact of the ketogenic diet on tumor growth and PDL1 expression in renal cell carcinoma

癌症代谢治疗

肿瘤免疫调节

Ketogenic diet significantly reduced the renal tumor cell growth proliferation. It also slowed down the tumor growth of ACHN xenografts in CD1 nude mice. We finally observed that a change in intratumo

NIAID Data Ecosystem30