Basic model of differentiation hierarchy of normal and leukemic cells.

NIAID Data Ecosystem2026-03-06 收录

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Basic model of differentiation hierarchy of normal and leukemic cells.

创建时间：

2009-09-11

Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition [miRNA]

白血病细胞分化

RNA调控网络

Treatment of leukemia cells with 1,25-dihydroxyvitamin D3 may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant

NIAID Data Ecosystem60

Long Intergenic Non-Coding RNA HOTAIRM1 Regulates Cell Cycle Progression During Myeloid Maturation in NB4 Promyelocytic Leukemia Cells

白血病细胞分化

非编码RNA调控

HOTAIRM1 is a long intergenic non-coding RNA located in the human HOXA gene cluster, with gene expression highly specific for maturing myeloid cells, particularly during all-trans retinoic acid (ATRA)

NIAID Data Ecosystem40

Comparing The Transcriptomes of Granulocytic and Macrophage Differentiated Forms of HL-60/S4 Cells. Homo sapiens

白血病细胞分化

转录组学分析

The acute myeloblastic leukemia cell line HL-60 can be differentiated in vitro from a rapidly growing promyelocytic form to a nongrowing form, resembling neutrophils with segmented (lobulated) nuclei,

NIAID Data Ecosystem30

Zinc finger protein 521 overexpression is a feature of MLL-rearranged acute myeloid leukemia and contributes to the maintenance of myeloid differentiation block

MLL重排白血病

白血病细胞分化

ZNF521 is a multiple zinc finger transcription factor previously identified because abundantly and selectively expressed in normal CD34+ hematopoietic stem and progenitor cells. From microarray datase

NIAID Data Ecosystem50

Reprogramming leukemic cells to terminal differentiation by inhibiting specific cyclin-dependent kinases in G(1)

白血病细胞分化

细胞周期蛋白依赖性激酶抑制

Some tumor cells can be stimulated to differentiate and undergo terminal cell division and loss of tumorigenicity. The in vitro differentiation of murine erythroleukemia (MEL) cells is a dramatic exam

PubMed Central2000-12-12 更新30

Basic model of differentiation hierarchy of normal and leukemic cells.

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