Characteristics of subjects included in this study.

Age, calendar age at entry-to-study; HIMS, Health In Men Study; P, two-sided P value; N/A, not available; (-), not applicable. Nominal variables are presented as numbers, while continuous variables are presented as mean ± standard deviation (SD). Nominal and continuous variables were compared between subjects in the gene expression study using Fisher’s exact test and Mann-Whitney U test, respectively. Characteristics of subjects included in this study.