C57BL6 mice were grafted with GL261-Dsred gliomas cells. One week after graft, 20 mg/ml of SMg was intra-veneously injected. treatment was performed once a week.
Quantification of interactions between CD8T cells and microglia TMEM119 cells in GL261-Dsred tumors at D21 and D28 post graft with or without SMg treatment.
Quantification of the distance between TMEM119 cells and vessels in GL261-DsRED tumors at D21 and D28 with or without SMg treatment.Images were generated by a light sheet microscope after brain cleari
Area and sphericity of LysM, CD11c and moDCs at D21 and D28 in GL261-DsRED tumors with or without SMg treatment. Images were obtained by two-photon imaging and analyzed with Imaris software.
Quantification of the distance between CD8 T cells and vessels in GL261-DsRED tumors at D21 and D28 with or without SMg treatment.Images were generated by a light sheet microscope after brain clearing