Inflammation is a hallmark of many human diseases, including pain, arthritis, atherosclerosis, obesity and diabetes, cancer, and neurodegenerative diseases. Although there are several successfully mar

NIAID Data Ecosystem90

Drug screening and genome editing in human pancreatic cancer organoids identifies drug-gene interactions and candidates for off-label treatment

胰腺癌药物筛选

药物-基因相互作用

Pancreatic cancer (PDAC) is a highly aggressive malignancy with poor response to chemotherapy. The identification of novel therapies is therefore urgently needed. Here we establish a human PDAC organo

NIAID Data Ecosystem30

Integration of the Drug–Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts

药物-基因相互作用

药物发现

The Drug-Gene Interaction Database (DGIdb, www.dgidb.org) is a web resource that provides information on drug-gene interactions and druggable genes from publications, databases, and other web-based so

NIAID Data Ecosystem90

Selected C. albicans genes downregulated in response to SBTX exposure.

基因表达调控

药物-基因相互作用

†Gene names and gene ontology according to the Candida albicans genome database (CGD). ‡ Absolute values<1.50 indicate that genes were downregulated in C. albicans in the presence of SBTX compared wit

NIAID Data Ecosystem30

Data File S17. YNL181W chemical genetics data

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