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A CLINICOHAEMATOLOGICAL STUDY IN PANCYTOPENIA

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NIAID Data Ecosystem2026-05-02 收录
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https://zenodo.org/records/13763017
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Objectives: 1.      Tostudythecausesandclinicalpresentationsofpancytopenia. 2.      ToevaluateHaematologicalparametersinpancytopeniaalongwithBoneMarrow Examination. Methods: AretrospectivestudywasconductedatdepartmentofPathologyfromJuly2017to Feb 2020. 20 cases of pancytopenia were evaluated clinically, along with haematological parameters. Results:Among20casesstudied,Maximumnumberofcases wasintheagegroupof21 -30 years (40%) with male predominance (1.2%). Most patients present with generalized weakness.Thecommonestbonemarrowfindingwasmegaloblasticerythroidhyperplasia. The commonest cause for pancytopenia was megaloblastic anaemia (60%) followed by aplastic anaemia (25%). Other causes of pancytopenia were hypersplenism, subleukemic leukemia, multiple myloma. Conclusion: Afterstudyingthese cases in present studywe have come onthe conclusion that the commonest cause of pancytopenia is megaloblastic anaemia. The detailed primary haematologicalinvestigationsofpatientswithpancytopeniahelptodeterminethecauseof the same, which is important for planning further investigation and crucial for treatment purpose.
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2024-09-14
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