Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

Name: Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals
Creator: Claeys, Arne; Van den Eynden, Jimmy
Published: 2021-02-01T00:00:00+08:00

Zenodo2021-02-01 更新2026-04-07 收录

癌症免疫原性

肿瘤突变

数据链接：

https://zenodo.org/record/4419691 数据链接链接失效反馈

官方服务：

资源简介：

Downstream data used for the analysis as reported in the corresponding manuscript.

提供机构：

Claeys, Arne; Van den Eynden, Jimmy

创建时间：

2021-02-01

Additional file 3 of IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation

胶质母细胞瘤

肿瘤突变

Additional file 3: Table 1. Clinical-pathological features and Tumor mutational burden of 39 GBMs enriched in giant cells. Cases are sorted by ID number. Table 2: List of somatic and germline mutation

DataCite Commons2021-12-25 更新100

Additional file 5: of Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs)

癌症基因组数据

肿瘤突变

Figures S3a and S3b. Estimation of LOH fraction and tumor content. Estimation of LOH fraction and tumor content using a Beta-Normal mixture model. Histograms show the distribution of major allele freq

DataCite Commons2020-08-30 更新80

Additional file 1 of Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival

癌症免疫治疗

肿瘤突变

Table S1. (summary of patient samples used for analysis), Table S2. (summary of patient clinical and DNA variant data), Table S3. (per-patient summary of driver variants and neoepitopes), Table S4. (m

DataCite Commons2020-08-25 更新60

Additional file 3 of Postoperative hyperprogression disease of pancreatic ductal adenocarcinoma after curative resection: a retrospective cohort study

胰腺癌

肿瘤突变

Additional file 3: Supplementary Fig. 1. Dot-box plots of TMB (A), MATH(B) and CNI(C) in PO-HPD and ER + LR groups. TMB: tumor mutational burden; MATH: mutant allele tumor heterogeneity; CNI: copy num

DataCite Commons2024-02-12 更新90

Mutations enriched in metastatic tumors relative to local disease (primary tumors and local recurrences) after filtering out variants of unknown significance.

肿瘤突变

统计学分析

Corrected p-values were calculated by permuting the met/local status of samples 1000 times, reflecting the probability of observing a more significant enrichment by chance. (XLSX)

NIAID Data Ecosystem60

Low immunogenicity of common cancer hot spot mutations resulting in false immunogenic selection signals

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