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Genome-wide maps of EWS-FLI1 binding sites and histone modification in murine Ewing sarcoma cells

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NIAID Data Ecosystem2026-05-26 收录
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We identified global DNA binding properties of EWS-FLI1 in mouse Ewing sarcoma. GGAA microsatellites were found as binding sites of EWS-FLI1 but with less frequency than that in human Ewing sarcoma, and genomic distribution is not conserved between human and mouse. Overall design: Examination of binding sites of EWS-FLI1, histone H3K27Ac and H3K27me3 in two Ewing sarcoma cell lines.

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2018-07-26
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