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Expression data of micRNA from spleen CD4+CD25+ Treg cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110994
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Treg plays a crucial immunomodulatory function. A few studies have confirmed the effects of parasite load on Treg cells phenotype and functions. We found that the plasmodium infection led to a particular micRNA profiles in Treg cells and influence the differentiation of Treg cells. We used microarrays to detail the global programme of micRNA expression and identified distinct classes of up-regulated micRNA during this process. The mice spleen CD4+CD25+ Treg cells were sorted by MACS sorting for micRNA extraction and hybridization on Affymetrix micRNA arrays.We set two groups to analysis. Control group is normal BALB/c mice. Experimental group is BALB/c mice infected with P.y 17XL.
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2021-10-02
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