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Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... Authors: Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. Deposit date: 2016-02-22 Release date: 2016-05-25 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.99 Å) Cite: The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016

嗜热栖热菌(Thermus thermophilus)70S核糖体复合物结构,该复合物包含信使RNA(mRNA)、甲酰甲硫氨酸转运RNA(tRNAfMet)、A位点(A-site)存在U-G错配的近同源赖氨酸转运RNA(tRNALys)以及抗生素巴龙霉素(paromomycin)。 描述项:16S核糖体RNA(16S ribosomal RNA)、23S核糖体RNA(23S ribosomal RNA)、30S核糖体蛋白S10(30S ribosomal protein S10)…… 作者:Rozov, A、Demeshkina, N、Yusupov, M、Yusupova, G 提交日期:2016-02-22 发布日期:2016-05-25 最后修改日期:2024-01-10 实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.99埃(Å) 引用文献:核糖体禁止密码子-反密码子螺旋第一位置的GU摆动构象。《核酸研究》(Nucleic Acids Res.),第44卷,2016年
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2016-02-22
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