Integrative network pharmacology, molecular docking, and transcriptomic investigation of potential mechanisms linking dietary fawu (provoking foods) to middle ear postoperative healing

Processed datasets, analysis scripts, and figures supporting the manuscript 'Dietary Fawu (Provoking Foods) and Middle Ear Postoperative Healing: An Integrative Network Pharmacology, Molecular Docking, and Transcriptomic Investigation of Potential Mechanisms'. This is a purely computational, hypothesis-generating study. Contents: (1) scripts/13_human_validation.py and scripts/14_gse17698_timeseries.py implementing the cross-cohort validation and healing time-series reanalysis; scripts/14_make_heatmap_png.py regenerates the human validation heatmap; (2) results/tables/*.csv with the 33 core targets, human otitis-media validation matrices (GSE125532 effusion, plus two pediatric acute otitis media PBMC cohorts GSE23140 and GSE27990) and rat tympanic-membrane healing validation (GSE17698), the cross-dataset consistency summary, and compound-target/disease-target mappings; (3) results/figures/*.svg and *.png including the four-layer human validation heatmap and GSE17698 healing trajectory; (4) results/tables/exposure_feasibility.md documenting the plasma-exposure vs docking-affinity argument; (5) the expanded manuscript and supplementary tables. All analyses were performed offline on publicly available GEO datasets.