Interactions Between Metabolic, Cognitive and Reward Processes in Appetite, 2016-2021

This archive contains the materials and results from experiments completed under the project entitled "Interactions between metabolic, cognitive and reward processes in appetite". Study 1 examined the effect of intra-nasal insulin on food intake, appetite and food reward and cognition in women with obesity and lean women. Study 2 examined the effect of the serotonin agonist mCPP on food intake, appetite and food reward and cognition in lean men and women. Study 3 examined the effect of Lisdexamfetamine dimesylate (LDX) in women with binge-eating symptoms. The findings have been published in: Schneider, E., Spetter, M. S., Martin, E., Sapey, E., Yip, K. P., Manolopoulos, K. N., ... & Higgs, S. (2022). The effect of intranasal insulin on appetite and mood in women with and without obesity: an experimental medicine study. International Journal of Obesity, 1-9. Schneider, E., Martin, E., Rotshtein, P., Qureshi, K. L., Chamberlain, S. R., Spetter, M. S., ... & Higgs, S. (2022). The effects of lisdexamfetamine dimesylate on eating behaviour and homeostatic, reward and cognitive processes in women with binge-eating symptoms: an experimental medicine study. Translational psychiatry, 12(1), 1-8. The results of the mCPP study are currently being written up for publication.