Fragment AZ-013 binding at the p53pT387/14-3-3 sigma interface

Fragment AZ-013 binding at the p53pT387/14-3-3 sigma interface Descriptor: 14-3-3 protein sigma, 4-(methylamino)-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ... Authors: Ottmann, C, Wolter, M, Guillory, X, Leysen, S, Genet, S, Somsen, B, Patel, J, Castaldi, P. Deposit date: 2019-08-20 Release date: 2020-06-17 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020片段AZ-013结合于p53pT387/14-3-3σ蛋白相互作用界面 描述项：14-3-3σ蛋白、4-(甲氨基)-7-异丙氧基-1-苯并噻吩-2-甲脒、氯离子…… 作者：Ottmann C、Wolter M、Guillory X、Leysen S、Genet S、Somsen B、Patel J、Castaldi P 提交日期：2019-08-20 发布日期：2020-06-17 最后修改日期：2024-11-06 实验方法：X射线衍射（1.9 Å） 引用文献：基于片段的蛋白相互作用稳定剂界面差异化靶向。J.Med.Chem.，63，2020