PD-1-PD-L1 Axis Activation Suppresses CD8+ T Cells and Improves Nephritis [RNA-seq]

PD-1+CD8+ T cells are exhausted in infection and cancer, their roles in lupus nephritis (LN) are largely unknown. PD-1+CD8+ and PD-1-CD8+ cells from spleens of NZB/W F1 mice were sorted for RNA-seq. Comparative gene expression profiling analysis of RNA-seq data for PD-1+CD8+ and PD-1-CD8+ cells from spleens of NZB/W F1 mice.