Identification and validation of novel ERBB2 (HER2, NEU) targets including genes

ChEBI2010-06-25 更新2026-07-21 收录

疾病靶点发现

基因验证研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-16445 数据链接链接失效反馈

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资源简介：

Identification and validation of novel ERBB2 (HER2, NEU) targets including genes

创建时间：

2010-06-25

PerturBench

单细胞扰动分析

疾病靶点发现

PerturBench是由Altos Labs开发的一个综合框架，旨在标准化细胞扰动分析领域的基准测试。该数据集包含多种扰动模式的数据，覆盖了化学和遗传扰动，以及组合扰动，数据量从数十万到数百万不等。数据集的创建过程涉及对现有数据集的筛选和预处理，以模拟真实世界的挑战。PerturBench主要应用于计算方法预测基因表达的扰动效应，旨在通过高吞吐量和高内容遗传及化学筛选，推动疾病靶点发现的研究。

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YAP1 and PRDM14 converge to regulate cell survival and tumorigenesis

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The transcriptional co-activator YAP1 oncogene is the downstream effector of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration and tumorigenesis. Multiple cancers are dep

NIAID Data Ecosystem50

Crystal structure of Aurora-A kinase in complex with N-Myc

激酶结构生物学

疾病靶点发现

Crystal structure of Aurora-A kinase in complex with N-Myc Descriptor: ADENOSINE-5'-DIPHOSPHATE, AURORA KINASE A, MAGNESIUM ION, ... Authors: Richards, M.W, Burgess, S.G, Bayliss, R. Deposit date: 201

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DataSheet_1_Proteomic Analyses Identify Therapeutic Targets in Hepatocellular Carcinoma.xlsx

肝细胞蛋白质组学

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Hepatocellular carcinoma (HCC) is the fourth cause of cancer-related mortality worldwide. While many targeted therapies have been developed, the majority of HCC tumors do not harbor clinically actiona

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疾病靶点发现

肿瘤药物靶点验证

The CTD² Dashboard compiles the Network-generated conclusions, or “observations,” associated with a specific gene, cell line, animal model, or perturbagen. It provides supporting evidence with links t

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Identification and validation of novel ERBB2 (HER2, NEU) targets including genes

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