Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice

NIAID Data Ecosystem2026-05-10 收录

神经炎症模型

脑血管病理学

数据链接：

https://immport.org/shared/study/SDY2338 数据链接链接失效反馈

官方服务：

资源简介：

To study if SARS-CoV-2 (MA10) infection in laboratory mice is a clinically relevant laboratory mouse model for SARS-CoV-2-mediated cerebrovascular pathology.

创建时间：

2025-10-30

Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA-sequencing of human cerebral cortex. Neurovascular dysfunction in GRN-associated frontotemporal dementia identified by single-nucleus RNA-sequencing of human cerebral cortex

神经退行性分子机制

脑血管病理学

Frontotemporal dementia (FTD) is the second most prevalent form of early-onset dementia, affecting predominantly frontal and temporal cerebral lobes. Heterozygous mutations in the progranulin gene (GR

NIAID Data Ecosystem70

Table_3_Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation.XLSX

胶质细胞研究

神经炎症模型

Microglia are central nervous system (CNS) resident immune cells that have been implicated in neuroinflammatory pathogenesis of a variety of neurological conditions. Their manifold context-dependent c

NIAID Data Ecosystem60

Brain microvessel-specific transcriptome profiling after severe cerebral hypoperfusion in mice. Brain microvessel-specific transcriptome profiling after severe cerebral hypoperfusion in mice

脑血管病理学

转录组学

Little is understood about the underlying cellular and molecular mechanisms related to brain microvessel damage and glial activation after severe cerebral hypoperfusion. Efforts to explore the relatio

NIAID Data Ecosystem30

MOESM1 of A comparison between the pathophysiology of multiple sclerosis and normal pressure hydrocephalus: is pulse wave encephalopathy a component of MS?

脑血管病理学

多发性硬化症比较研究

Additional file 1. Blood flow and pulsation measurements.

NIAID Data Ecosystem60

Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia: LPS Experiment RNA-Seq Data. Inducible cell-specific mouse models for paired epigenetic and transcriptomic studies of microglia and astroglia: LPS Experiment RNA-Seq Data

单细胞多组学

神经炎症模型

Studies of neuroepigenetic mechanisms in health and disease are hindered by a lack of approaches to analyze both the transcriptome and epigenome of specific cell types isolated from the complex milieu

NIAID Data Ecosystem40

Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice

资源简介：

相关数据集