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Trenscriptome analysis of TSLP stimulated regulatory T cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE189713
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Regulatory T cells are indispensable for the immune homeostasis. Recent studies revealed the crucial roles of tissue factors; however, the roles of epithelial cell derived cytokine TSLP in the maturation of regulatory T cells are not adressed. Here, we report that TSLP activates mTOR signaling to mature regulatory T cells to maintain large intestine homeostasis. mRNA obtained from PBS or TSLP stimulated regulatory T cells
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2023-02-06
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