The IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma (MM)

NIAID Data Ecosystem2026-05-01 收录

多发性骨髓瘤小鼠模型

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE220828 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-12-06

A Novel Mouse Model for Multiple Myeloma (MOPC315.BM) That Allows Noninvasive Spatiotemporal Detection of Osteolytic Disease

多发性骨髓瘤小鼠模型

溶骨性疾病活体成像

Multiple myeloma (MM) is a lethal human cancer characterized by a clonal expansion of malignant plasma cells in bone marrow. Mouse models of human MM are technically challenging and do not always reca

NIAID Data Ecosystem50

Homozygous iMycCa transgenic mice as a model of plasma B-cell lymphomas

多发性骨髓瘤小鼠模型

B细胞淋巴瘤转录组特征

in order to document molllecular signature of iMycCa B-cell lymphomas, RNA sequecing of CD138+ and CD138-B-cell lymphomas was performed and normalized expression data was obtained for all protein-codi

NIAID Data Ecosystem20

Transcriptomic profiling of normal plasma cells and MM models using bulk RNA-Seq. Transcriptomic profiling of normal plasma cells and MM models using bulk RNA-Seq

多发性骨髓瘤小鼠模型

BulkRNA-Seq转录组学

NRAS Q61 mutations are prevalent in advanced/relapsed multiple myeloma (MM) and correlate with poor patient outcomes. Thus, we generated a novel MM model by conditionally activating expression of endo

NIAID Data Ecosystem20

B-cell-Specific Wwox Deletion Promotes Plasmablastic Tumor Development and Pro-Inflammatory Signatures in a Myeloma Mouse Model

多发性骨髓瘤小鼠模型

B细胞肿瘤转录组

Deletions and translocations affecting WWOX accompanied by loss of expression are frequently observed in B cell neoplasms and are linked to poor prognosis. Our previous research showed that Wwox delet

NIAID Data Ecosystem40

Homozygous iMycCα transgenic mice as a model of plasma B-cell lymphomas. Homozygous iMycCα transgenic mice as a model of plasma B-cell lymphomas

多发性骨髓瘤小鼠模型

B细胞淋巴瘤转录组分析

in order to document molllecular signature of iMycCα B-cell lymphomas, RNA sequecing of CD138+ and CD138-B-cell lymphomas was performed and normalized expression data was obtained for all protein-codi

NIAID Data Ecosystem20

The IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma (MM)

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