Adenovirus E1A oncogene induces re-replication of cellular DNA and alters DNA replication dynamics

ChEBI2013-05-22 更新2026-07-21 收录

病毒致癌机制

DNA复制调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-47140 数据链接链接失效反馈

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Adenovirus E1A oncogene induces re-replication of cellular DNA and alters DNA replication dynamics

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2013-05-22

Identification of cis elements for temporal and spatial control of DNA replication [Repli-seq epha4]

DNA复制调控

染色质结构

DNA replication occurs in units of chromatin higher order organization (Topologically Associating Domains, or TADs; replication domains, or RDs), which self-organize in 3D into sub-nuclear compartment

NIAID Data Ecosystem50

Crystal structure of YabA amino-terminal domain from Bacillus subtilis

蛋白质晶体

DNA复制调控

Crystal structure of YabA amino-terminal domain from Bacillus subtilis Descriptor: Initiation-control protein YabA Authors: Cherrier, M.V, Bazin, A, Jameson, K.H, Wilkinson, A.J, Noirot-Gros, M.F, Ter

Protein Data Bank Japan2024-05-08 更新50

Role for DNA exonuclease V resection activity of RecBCD in control of aberrant chromosomal replication initiation in Escherichia coli

DNA复制调控

RecBCD外切酶功能

Replication of the circular bacterial chromosome is initiated from a locus oriC with the aid of an essential protein DnaA. One approach to identify factors acting to prevent aberrant oriC-independent

NIAID Data Ecosystem40

Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1

病毒致癌机制

癌症干细胞分化

Merkel cell carcinoma (MCC) is a highly aggressive skin cancer associated with integration of Merkel cell polyomavirus (MCPyV). MCPyV-encoded T-antigens (TAs) are pivotal for sustaining MCC’s oncogeni

NIAID Data Ecosystem50

Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by Marek's disease oncoprotein, Meq

病毒致癌机制

基因调控

Marek’s disease (MD) is an economically significant disease in chickens caused by the highly oncogenic Marek’s disease virus (MDV). A major unanswered question is the mechanism of MDV-induced tumor fo

agdatacommons.nal.usda.gov2024-09-29 更新40

Adenovirus E1A oncogene induces re-replication of cellular DNA and alters DNA replication dynamics

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