Six scenarios were considered for the computer simulations. In the scenarios A and B it is tested whether metastases do metastasize or not. In the scenarios C and D it is additionally investigated whe
To evaluate the in vivo metastatic activity of five different melanoma cell lines (LCP, LCM, WM266, SKMel28 and A375), we completed intra-cardiac injection of 1x106 luminescent cells in NOD-SCID mice.
The mouse renal cancer cell line RENCA was serially passaged in vivo using multiple implantation strategies (called Kidney, Tail and Lung) designed to replicate different aspects of primary tumour gro