The enzyme was preincubated for 5 min at 35°C with the various reagents before addition of the substrate. Each reagent was added at the final concentration as indicated.
Color scale indicates drug potency: darker blue = more potent, lighter blue = less potent. Anti-amoebic activity classified based on EC50 value as: Very high (0.001–0.999 μM), High (1.000–4.999 μM), M
Current treatment for combatting Chagas disease, a life-threatening illness caused by the kinetoplastid protozoan parasite Trypanosoma cruzi is inadequate, and thus the discovery of new antipar
Half maximal effective concentration (mg mL-1; EC50) obtained for protein fractions of Spigelia anthelmia against Haemonchus contortus eggs and larvae.
Chagas' disease is a parasitic disease with unsatisfactory treatment, mainly in chronic stage. This study aimed to evaluate the trypanocidal activity and action mechanisms of α/β-amyrin and its semi-s
