Cell-autonomous hepatocyte-specific GP130 signalling
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https://www.ncbi.nlm.nih.gov/sra/SRP276384
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资源简介：
Members of the IL-6 cytokine family contribute to inflammatory and regenerative processes. Engagement of the signalling receptor subunit gp130 is common to almost all members of the family. In the liver, all major cell types respond to IL-6, making it difficult to delineate cell type-specific effects of IL-6 type cytokines. We therefore generated mouse models for liver cell type-specific analysis of IL-6 signalling. We phenotyped these mice using multi-omics approaches, immunophenotyping and a bacterial infection model.
创建时间：
2020-08-07
