The ureters of Col17a1-KO mice at 4 days after unilateral ureteral obsruction

Collagen 17A1 (COL17A1) is induced in urothelium under disease conditions of urinary system organs, such as chronic nephritis and urinary obstruction. Thus, the ureters of Col17a1-knock out (KO) mice were injured by unilateral ureteral obsruction (UUO), and the gene expression was compared with those of wild-tyoe (WT). The ureters were collected from 2-month-old Col17a1-KO mice (C57BL/6N background) at 4 days after UUO. And then, RNA was collected and gene expression was analyzed.