A receptor-independent, data-driven framework for broad-spectrum phage cocktails against vancomycin-resistant Enterococcus faecium

Table S1 Phages included in this study. Table S2 Enterococcus strains included in this study. Table S3 The score of phage infection network on Enterococcus strains with spot assay. Table S4 Information on the mutation sites of the phage-resistant strains. Table S5 Plasmids and primers for complemented strain construction. Table S6 Antibiotic sensitivity profile of the phage-resistant strains. Table S7 Pairwise phage co-infection assays across 6 strains. Table S8 Information of candidate phage cocktail library. Table S9 Inhibition rates of 16 phage cocktails against 157 E. faecium strains. Table S10 Analysis of non-inhibition of discordant strains (theoretically susceptible, actually resistant) by phage cocktails (k=6).表S1 本研究纳入的噬菌体 表S2 本研究纳入的肠球菌菌株 表S3 基于斑点试验的噬菌体-肠球菌菌株感染网络评分 表S4 抗噬菌体菌株的突变位点信息 表S5 互补菌株构建所用的质粒与引物 表S6 抗噬菌体菌株的抗生素敏感性谱 表S7 6株菌株间的噬菌体两两共感染试验 表S8 候选噬菌体组合文库信息 表S9 16种噬菌体组合对157株屎肠球菌（Enterococcus faecium）的抑制率 表S10 6组噬菌体组合对表型不符菌株（理论易感、实际耐药）的无抑制作用分析