Supplementary Material for: Endocavitary right ventricular cardiac metastasis of a lung adenocarcinoma treated by surgery : a novel multimodal therapeutic approach

Cardiac metastasis (CM) is a rare lung cancer location. It often remain clinically silent but may cause life threatening complications.
Better survival rate thanks to the immunotherapy revolution and the improving performance of imaging lead to an increasing number of CM diagnosis.
We report a case of a fifty-four-years old woman who was diagnosed with a stage IIIa non-small cells lung cancer. She developed a right ventricular cardiac metastasis during treatment by immunotherapy after concurrent chemoradiotherapy.
Cardiac magnetic resonance imaging concluded to an endocavitary tissular lesion at the RV apex. A surgical complete resection consisting of a right ventriculotomy was performed.
Thanks to immunotherapy and more performing imaging, similar cases are more frequent. Our case report also highlights the fact that CM surgery has to be considered as a successful therapeutic option in those oligo-progression situations. Guidelines on the management and treatment of lung cancer CM are needed as well as larger studies to evaluate the benefit from a surgical treatment on the survival rate.

心包转移（CM）是一种罕见的肺癌发病位置。该病症通常临床表现为沉默，但可能引发危及生命的并发症。得益于免疫治疗革命和影像学性能的不断提升，心包转移的诊断病例数量呈现增长趋势。本文报道了一例54岁女性患者的病例，该患者在经过同步放化疗后，在接受免疫治疗过程中发生了右侧心室心包转移。心脏磁共振成像检查结果显示，在右心室尖部存在心内组织病变。通过右心室切开术进行了一次完全性切除手术。得益于免疫治疗及更高效的影像学技术，类似病例的发生频率有所增加。本病例报告亦凸显了心包转移手术在寡进展情况下的成功治疗选择。此外，对于肺癌心包转移的管理和治疗指南，以及更大规模的研究以评估手术治疗对生存率的益处，均亟待制定。