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TTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced Cancers

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NIAID Data Ecosystem2026-03-11 收录
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https://www.omicsdi.org/dataset/ecrin-mdr-crc/2332975
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This is a phase 1/1b study of TTX-030 in combination therapy, an antibody that inhibits CD39 enzymatic activity, leading to accumulation of pro-inflammatory adenosine triphosphate (ATP) and reduction of immunosuppressive adenosine, which may change the tumor microenvironment and promote anti-tumor immune response. This trial will study the safety, tolerability, pharmacokinetics, pharmacodynamics and anti-tumor activity of TTX-030 in combination with immunotherapy and/or standard chemotherapies.
创建时间:
2020-03-15
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