Tip60-mediated H2A.Z acetylation is required for neuronal fate specification and bivalent gene activation [ATAC-Seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP332244
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资源简介：
Examination of the effects of Tip60/Kat5 depletion on chromatin accessibility dynamics during Ascl1-mediated direct reprogramming of mouse embryonic fibroblasts (MEFs) into induced neuronal cells. Overall design: Genome-wide chromatin accessibility (ATAC-seq) determined for rtTA control or Ascl1-transduced MEFs co-expressing shRNA targeting Tip60 (shTip60), shRNA targeting H2A.Z (shH2AZ), or non-targetng control shRNA (shNTC) at day2 and/or day5 of iN cell reprogramming.
创建时间：
2022-12-21
